Evaluation of antibacterial potentials of Parthenium hysterophorus L. leaf extract against some pathogenic and nonpathogenic bacteria
Abstract
Background: The herb, P. hysterophorus L. has been used in folk medicine for many years to treat neurological disorders, inflammation, fever and malaria. This study aimed to evaluate the antibacterial activity of P. hysterophorus L. leaf extracts against some pathogenic and nonpathogenic bacterial strains.
Methods: Methanol and chloroform extracts of P. hysterophorus L. leaf were applied against pathogenic Vibrio (V.) parahaemolyticus ATCC 17802, Escherichia coli 0157 ATCC 43894, Sarcina (S.) lutea IFO 3232) and nonpathogenic Bacillus (B.) subtilis IFO 3026 strains by agar well diffusion assay. Visible zones of inhibition were measured.
Results: The methanol and chloroform extracts of P. hysterophorus leaf exhibited remarkable antibacterial activity against all three pathogenic (V. parahaemolyticus, E. coli 0157, S. lutea) and nonpathogenic (B. subtilis) bacterial strains. Chloroform solvent extract of P. hysterophorus leaves showed highest zone of inhibition (23 mm) against gram positive pathogenic S. lutea and methanolic leaf extract showed highest zone of inhibition (26 mm) against B. subtilis. The lowest zone of inhibition was observed for gram negative pathogenic V. parahaemolyticus in the response of methanolic (9 mm) and the chloroform (10mm) leaf extract.
Conclusion: The findings of this study suggest that, leaf extracts of Parthenium hysterophorus L. could be a potential source of antibacterial agents to cope with antibiotic resistance and new drug discovery.
Downloads
Copyright (c) 2021 Bangladesh Society for Veterinary Medicine
This work is licensed under a Creative Commons Attribution 4.0 International License.