Investigation of antibiotic resistance pattern of Staphylococcus aureus in clinical samples of animals and humans from selective areas of Bangladesh

M. A. Islam; M. S. Uddin; M. J. Islam; M. U.  Ahmed; M. M. Alam

M. A. Islam Department of Medicine, Faculty of Veterinary Medicine & Animal Science, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur-1706, Bangladesh
M. S. Uddin Department of Medicine, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
M. J. Islam Department of Microbiology & Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
M. U. Ahmed Department of Medicine, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
M. M. Alam Department of Medicine, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh

Keywords: Penicillin, Oxytetracycline, Oxacillin, Clinicians, Veterinarian, Antibiogram

Abstract

Background: Staphylococcus aureus (S. aureus) is a potential pathogen responsible for producing various infectious diseases. Determination of the prevalence of S. aureus infections both in animals and humans and elucidation of their antibiotic resistance pattern is crucial. The objective of this study was to find out the prevalence of Staphylococcal diseases in animals and humans, and their resistance pattern to commonly used antibiotics.

Methods: A total of 100 animal and 100 human clinical samples were analyzed by traditional method. The S. aureus was identified by their cultural characteristics, gram’s staining, and catalase and coagulase tests. Antibiotic resistance pattern of the isolates was determined by disc diffusion method using various types of antibiotics.

Results: The prevalence of S. aureus in animals and humans were 54% and 40%, respectively. S. aureus isolates of animal origin were highly resistant against penicillin (64.81%) and oxytetracycline (42.59%), and the lowest resistance was against oxacillin (7.40 %). S. aureus isolates from human were also showed a higher percentage of resistance against penicillin (87.5%) then oxacillin, cloxacillin, amoxicillin (37.5% each), and lowest resistance was observed against fusidic acid (5%).

Conclusion: The findings of this study will certainly help veterinary clinicians or physicians to select appropriate antibiotics like oxacillin and fusidic acid for the treatment of different types of staphylococcal infections.

DOI: https://doi.org/10.33109/bjvmjj21vph1

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